Nine Steps to Personalised Therapy: The Art and Science of Anti-Cancer Drug Dosing.
Here we review the issues around decision-making processes by an oncology physician to arrive at the most appropriate dose for each patient. This information is valuable to a range of health professionals, including nurses, pharmacists and administrators, as well as patients, to allow them to understand medical oncologists’ decisions and support them where appropriate. Then we provide 9 principles that should guide cancer physicians in determining the most appropriate individual dose to provide the best possible outcomes. Lastly, we suggest future improvements towards optimal cancer drug dosing, and education and training recommendations.